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IN Science & Technology ON 12 Oct, 2016
Each year, there are nearly 4,000 Americans awaiting heart transplants but only 2,000 of them receive hearts. What happens to the others? Of course, they pass away.
Even if a patient receives a heart, there are various complications and the body can also throw off an auto-immune reaction which could result in the body's own cells damaging the new heart tissue.
To figure out this problem, researchers and scientists have been trying to use patient's own body cells to create different organs of the body. And the great news is, they made it happen up to some extent.
They've been able to get one step closer to making a synthetically created human heart using adult stem cells.
Human adult skin cells were used in regenerating a functional human heart. It could prove to be very useful for patients diagnosed with heart failure.
This is the best that scientists could do without setting off an auto-immune response in the whole body.
But that didn't work out and they rejected 73 donor hearts. Later, they tried out adult skin cells with the help of a new technique.
They modified the messenger RNA of the adult skin cells and turned them into pluripotent stem cells. These stem cells can take the shape of any human cell belonging to any organ of the body.
After infusing the stem cells with the cardiac cells, a nutrient solution was given to the cells for nearly 2 weeks. The scientists started noticing an immature structure of the human heart was forming.
The scientists wanted to start the regular rhythm of the heart so electric shocks were passed to make it beat.
Although, the structure of the heart is ready but they aren't sure of the heart being functionally fit to be transplanted. The scientists are making a few changes to make it better.
If this technique becomes fully successful, it would be a revolutionary achievement.
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